Balbino Alarcón : rechercher sur Z-Library

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1H-NMR analysis of CD3-ϵ reveals the presence of turn-helix structures around the ITAM motif in an otherwise random coil cytoplasmic tail

Aldo Borroto, M. Angeles Jiménez, Balbino Alarcón, Manuel Rico

Journal:

Biopolymers

Année:

1997

Langue:

english

Fichier:

PDF, 191 KB

english, 1997

Assembly of the TCR/CD3 complex: CD3ϵ/δ and CD3ϵ/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model

Ester San José, Almudena G. Sahuquillo, Rafael Bragado, Balbino Alarcón

Journal:

European Journal of Immunology

Année:

1998

Langue:

english

Fichier:

PDF, 188 KB

english, 1998

Apoptosis-resistant T cells have a deficiency in NF-κB-mediated induction of Fas ligand transcription

Emma Teixeiro, Almudena García-Sahuquillo, Balbino Alarcón, Rafael Bragado

Journal:

European Journal of Immunology

Année:

1999

Langue:

english

Fichier:

PDF, 167 KB

english, 1999

Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner

Aldo Borroto, Diana Gil, Pilar Delgado, Miguel Vicente-Manzanares, Andrés Alcover, Francisco Sánchez-Madrid, Balbino Alarcón

Journal:

European Journal of Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 191 KB

english, 2000

Inhibition of natural killer cytotoxicity by extracellular ppp(A2′p5′)nA oligonucleotides

Balbino Alarcón, Juan M. Redondo, Harald Bugany, Luis Carrasco, Manuel Fresno

Journal:

International Journal of Immunopharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 596 KB

english, 1988

Hexose-modified anti-viral analogues of uridine 5′-disphosphate glucose derivatives

José Fiandor, María-Teresa Garcìa-López, Federico G De Las Heras, Paloma P Méndez-Castrillón, Ana San Félix, Balbino Alarcón, Luis Carrasco

Journal:

European Journal of Medicinal Chemistry

Année:

1987

Langue:

english

Fichier:

PDF, 1.81 MB

english, 1987

T lymphocyte receptor deficiencies

Dietmar J. Kappes, Balbino Alarcón, JoséR. Regueiro

Journal:

Current Opinion in Immunology

Année:

1995

Langue:

english

Fichier:

PDF, 688 KB

english, 1995

Interaction between the N-terminal SH3 domain of Nckα and CD3ɛ-derived peptides: Non-canonical and canonical recognition motifs

Clara M. Santiveri, Aldo Borroto, Luis Simón, Manuel Rico, Balbino Alarcón, M. Angeles Jiménez

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2009

Langue:

english

Fichier:

PDF, 689 KB

english, 2009

Initiation of TCR signaling: regulation within CD3 dimers

Balbino Alarcón, Diana Gil, Pilar Delgado, Wolfgang W. A. Schamel

Journal:

Immunological Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 109 KB

english, 2003

The extracellular part of ζ is buried in the T cell antigen receptor complex

Susana Minguet, Mahima Swamy, Elaine P. Dopfer, Eva Dengler, Balbino Alarcón, Wolfgang W.A. Schamel

Journal:

Immunology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 677 KB

english, 2008

The immunological synapse: a cause or consequence of T-cell receptor triggering?

Balbino Alarcón, David Mestre, Nuria Martínez-Martín

Journal:

Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 218 KB

english, 2011

CD3δ couples T-cell receptor signalling to ERK activation and thymocyte positive selection

Delgado, Pilar, Fernández, Edgar, Dave, Vibhuti, Kappes, Dietmar, Alarcón, Balbino

Journal:

Nature

Année:

2000

Langue:

english

Fichier:

PDF, 429 KB

english, 2000

An endoplasmic reticulum retention signal in the CD3ɛ chain of the T-cell receptor

Mallabiabarrena, Arrate, Fresno, Manuel, Alarcón, Balbino

Journal:

Nature

Année:

1992

Fichier:

PDF, 563 KB

1992

Handing over the baton

Alarcón, Balbino, Martínez-Martin, Nuria

Journal:

Immunology & Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 232 KB

english, 2010

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling

Delgado, Pilar, Cubelos, Beatriz, Calleja, Enrique, Martínez-Martín, Nuria, Ciprés, Angel, Mérida, Isabel, Bellas, Carmen, Bustelo, Xosé R, Alarcón, Balbino

Journal:

Nature Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 708 KB

english, 2009

T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity

Alarcón, Balbino, Swamy, Mahima, van Santen, Hisse M, Schamel, Wolfgang W A

Journal:

EMBO reports

Année:

2006

Langue:

english

Fichier:

PDF, 291 KB

english, 2006

Megalomicin Inhibits HIV-1 Replication and Interferes with gp160 Processing

Ester San José, M.Angeles Muñoz-Fernández, Balbino Alarcón

Journal:

Virology

Année:

1997

Langue:

english

Fichier:

PDF, 520 KB

english, 1997

Abnormal T cells from MRL/Mp-lpr/lpr mice do not respond to anti-T-cell-receptor antibody or tumor promoter and calcium lonophore A23187 despite the presence of the T-cell-receptor complex and protein kinase c

Man-Sun Sy, Peter T.H. Wang, Shyr-Te Ju, Kathryn M. Weston, Balbino Alarcon, Cox Terhorst, Edward T.H. Yeh

Journal:

Cellular Immunology

Année:

1988

Langue:

english

Fichier:

PDF, 1.66 MB

english, 1988

Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling

María José Caloca, Pilar Delgado, Balbino Alarcón, Xosé R. Bustelo

Journal:

Cellular Signalling

Année:

2008

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2008

A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes

Mahima Swamy, Susana Minguet, Gabrielle M. Siegers, Balbino Alarcón, Wolfgang W.A. Schamel

Journal:

Journal of Immunological Methods

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

Megalomycin C, a macrolide antibiotic that blocks protein glycosylation and shows antiviral activity

Balbino Alarcón, M.Eugenia González, Luis Carrasco

Journal:

FEBS Letters

Année:

1988

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1988

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

Susana Minguet, Mahima Swamy, Balbino Alarcón, Immanuel F. Luescher, Wolfgang W.A. Schamel

Journal:

Immunity

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

Nuria Martínez-Martín, Elena Fernández-Arenas, Saso Cemerski, Pilar Delgado, Martin Turner, John Heuser, Darrell J. Irvine, Bonnie Huang, Xosé R. Bustelo, Andrey Shaw, Balbino Alarcón

Journal:

Immunity

Année:

2011

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2011

Increased Sensitivity of Antigen-Experienced T Cells through the Enrichment of Oligomeric T Cell Receptor Complexes

Rashmi Kumar, María Ferez, Mahima Swamy, Ignacio Arechaga, María Teresa Rejas, Jose M. Valpuesta, Wolfgang W.A. Schamel, Balbino Alarcon, Hisse M. van Santen

Journal:

Immunity

Année:

2011

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2011

A conformation- and avidity-based proofreading mechanism for the TCR–CD3 complex

Wolfgang W.A. Schamel, Ruth M. Risueño, Susana Minguet, Angel R. Ortíz, Balbino Alarcón

Journal:

Trends in Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 156 KB

english, 2006

Recruitment of Nck by CD3ϵ Reveals a Ligand-Induced Conformational Change Essential for T Cell Receptor Signaling and Synapse Formation

Diana Gil, Wolfgang W.A. Schamel, Marı́a Montoya, Francisco Sánchez-Madrid, Balbino Alarcón

Journal:

Cell

Année:

2002

Langue:

english

Fichier:

PDF, 640 KB

english, 2002

Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism

Ester San José, Aldo Borroto, Florence Niedergang, Andrés Alcover, Balbino Alarcón

Journal:

Immunity

Année:

2000

Langue:

english

Fichier:

PDF, 276 KB

english, 2000

Organization of the resting TCR in nanoscale oligomers

Schamel, Wolfgang W. A., Alarcón, Balbino

Journal:

Immunological Reviews

Année:

2013

Langue:

english

Fichier:

PDF, 655 KB

english, 2013

Uridine 5'-diphosphate glucose analogs. Inhibitors of protein glycosylation that show antiviral activity

Camarasa, Maria Jose, Fernandez-Resa, Piedad, Garcia-Lopez, Maria Teresa, De las Heras, Federico G., Mendez-Castrillon, Paloma P., Alarcon, Balbino, Carrasco, Luis

Journal:

Journal of Medicinal Chemistry

Année:

1985

Langue:

english

Fichier:

PDF, 829 KB

english, 1985

Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease

Larive, Romain M., Moriggi, Giulia, Menacho-Márquez, Mauricio, Cañamero, Marta, Álava, Enrique de, Alarcón, Balbino, Dosil, Mercedes, Bustelo, Xosé R.

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 3.01 MB

english, 2014

The T-Cell Receptor γ Chain-CD3 complex: Implication in the Cytotoxic Activity of a CD3+CD4-CD8-Human Natural Killer Clone

Balbino Alarcon, Jan De Vries, Carolyn Pettey, Arthur Boylston, Hans Yssel, Cox Terhorst and Hergen Spits

Journal:

Proceedings of the National Academy of Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1987

Evolutionary Relationship between the T3 Chains of the T-Cell Receptor Complex and the Immunoglobulin Supergene Family

Daniel P. Gold, Hans Clevers, Balbino Alarcon, Sabrina Dunlap, Jiri Novotny, Alan F. Williams and Cox Terhorst

Journal:

Proceedings of the National Academy of Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 1.04 MB

english, 1987

Multivalent Structure of an α β T Cell Receptor

Gemma Fernandez-Miguel, Balbino Alarcon, Antonio Iglesias, Horst Bluethmann, Melchor Alvarez-Mon, Eva Sanz and Antonio de la Hera

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.87 MB

english, 1999

The CD3 Conformational Change in the γδ T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing

Dopfer, Elaine P., Hartl, Frederike A., Oberg, Hans-Heinrich, Siegers, Gabrielle M., Yousefi, O. Sascha, Kock, Sylvia, Fiala, Gina J., Garcillán, Beatriz, Sandstrom, Andrew, Alarcón, Balbino, Regueiro

Journal:

Cell Reports

Année:

2014

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2014

Synthesis and antiviral evaluation of nucleosides of 5-methylimidazole-4-carboxamide

Alonso, Rosario, Andres, J. Ignacio, Garcia-Lopez, M. Teresa, De las Heras, Federico G., Herranz, Rosario, Alarcon, Balbino, Carrasco, Luis

Journal:

Journal of Medicinal Chemistry

Année:

1985

Langue:

english

Fichier:

PDF, 731 KB

english, 1985

Retroviral Vector-Mediated Expression in Primary Human T Cells of an Endoplasmic Reticulum-Retained CD4 Chimera Inhibits Human Immunodeficiency Virus Type-1 Replication

José, Ester San, Muñoz-Fernández, María Angeles, Alarcón, Balbino

Journal:

Human Gene Therapy

Année:

1998

Langue:

english

Fichier:

PDF, 11.66 MB

english, 1998

Construction of Retroviral Vectors Carrying Human CD3 γ cDNA and Reconstitution of CD3 γ Expression and T Cell Receptor Surface Expression and Function in a CD3 γ -Deficient Mutant T Cell Line

Sun, Ji-Yao, Pacheco-Castro, Alberto, Borroto, Aldo, Alarcon, Balbino, Alvarez-Zapata, David, Regueiro, Jose R.

Journal:

Human Gene Therapy

Année:

1997

Langue:

english

Fichier:

PDF, 4.60 MB

english, 1997

Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains

Beck-García, Katharina, Beck-García, Esmeralda, Bohler, Sheila, Zorzin, Carina, Sezgin, Erdinc, Levental, Ilya, Alarcón, Balbino, Schamel, Wolfgang W.A.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2015

Preface to special issue on nanoscale membrane organisations

Alarcón, Balbino, Reth, Michael, Schamel, Wolfgang

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 231 KB

english, 2015

T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation

Risueño, Ruth M., Schamel, Wolfgang W. A., Alarcón, Balbino, Kanellopoulos, Jean

Journal:

PLoS ONE

Année:

2008

Langue:

english

Fichier:

PDF, 282 KB

english, 2008

The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

Menacho-Márquez, Mauricio, García-Escudero, Ramón, Ojeda, Virginia, Abad, Antonio, Delgado, Pilar, Costa, Clotilde, Ruiz, Sergio, Alarcón, Balbino, Paramio, Jesús M., Bustelo, Xosé R., Hynes, Nancy

Journal:

PLoS Biology

Année:

2013

Langue:

english

Fichier:

PDF, 9.19 MB

english, 2013

TCR Nanoclusters as the Framework for Transmission of Conformational Changes and Cooperativity

Blanco, Raquel, Alarcón, Balbino

Journal:

Frontiers in Immunology

Année:

2012

Langue:

english

Fichier:

PDF, 964 KB

english, 2012

End-binding protein 1 controls signal propagation from the T cell receptor

Martín-Cófreces, Noa B, Baixauli, Francesc, López, María J, Gil, Diana, Monjas, Alicia, Alarcón, Balbino, Sánchez-Madrid, Francisco

Journal:

The EMBO Journal

Année:

2012

Langue:

english

Fichier:

PDF, 3.06 MB

english, 2012

IMMUNOSUPPRESSION-INDEPENDENT ROLE OF REGULATORY T CELLS AGAINST HYPERTENSION-DRIVEN RENAL DYSFUNCTIONS

Fabbiano, Salvatore, Menacho-Márquez, Mauricio, Robles-Valero, Javier, Pericacho, Miguel, Matesanz-Marín, Adela, García-Macías, Carmen, Sevilla, María A., Montero, M. J., Alarcón, Balbino, López-Novoa

Journal:

Molecular and Cellular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 5.41 MB

english, 2015

RRas2, RhoG and T-cell phagocytosis

Alarcón, Balbino, Martínez-Martín, Nuria

Journal:

Small GTPases

Année:

2012

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2012

MTOC Translocation Modulates IS Formation and Controls Sustained T Cell Signaling

Noa B. Martín-Cófreces, Javier Robles-Valero, J. Román Cabrero, María Mittelbrunn, Mónica Gordón-Alonso, Ching-Hwa Sung, Balbino Alarcón, Jesús Vázquez and Francisco Sánchez-Madrid

Journal:

The Journal of Cell Biology

Année:

2008

Langue:

english

Fichier:

PDF, 3.68 MB

english, 2008

CD3ε recruits Numb to promote TCR degradation

Martin-Blanco, Nadia, Jiménez Teja, Daniel, Bretones, Gabriel, Borroto, Aldo, Caraballo, Michael, Screpanti, Isabella, León, Javier, Alarcón, Balbino, Canelles, Matilde

Journal:

International Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 8.23 MB

english, 2016

Familial Defect in the Surface Expression of the T-Cell Receptor–CD3 Complex

Alarcon, Balbino, Regueiro, Jose Ramon, Arnaiz-Villena, Antonio, Terhorst, Cox

Journal:

Boston Medical and Surgical Journal

Année:

1988

Langue:

english

Fichier:

PDF, 6.10 MB

english, 1988

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Blas-Rus, Noelia, Bustos-Morán, Eugenio, Pérez de Castro, Ignacio, de Cárcer, Guillermo, Borroto, Aldo, Camafeita, Emilio, Jorge, Inmaculada, Vázquez, Jesús, Alarcón, Balbino, Malumbres, Marcos, Martí

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 4.40 MB

english, 2016

The Allostery Model of TCR Regulation

Schamel, Wolfgang W. A., Alarcon, Balbino, Höfer, Thomas, Minguet, Susana

Journal:

The Journal of Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2017